Gebruiker: RaineSturtevant648

Uit Mulckhuijse
Versie door RaineSturtevant648 (Overleg | bijdragen) op 9 mrt 2012 om 01:18 (Pagina aangemaakt: ''Signs or symptoms of serotonin syndrome''' Irritability, Delirium, Change, Fits, Restlessness, Increased middle rate, Sweating, Shivering, Tremor, Mental status changes, Restle...)

(wijz) ← Oudere versie | Huidige versie (wijz) | Nieuwere versie → (wijz)
Ga naar: navigatie, zoeken

Signs or symptoms of serotonin syndrome'

Irritability, Delirium, Change, Fits, Restlessness, Increased middle rate, Sweating, Shivering, Tremor, Mental status changes, Restlessness, Increased reflexes, Increased reflexes, Stiffness, Moving, Pain in the belly, Diarrhea, Sweating, Increased temperature, Hypertension. Just about all these are signs of serotonin syndrome. All can look usually in the 1st 24 hours soon after taking a particular o.d. of serotonin drugs. This symptoms take cognitive degree, visceral worried system stage and SoNS stage. Serotonin toxicity look frequently after o.d. of serotonin drugs as well as drug combination which increase synaptic serotonin. Drugs that tend to be understand to stimulate high levels of serotonin are: MAOIs, TCAs, SSRIs, SNRIs, Bupropion, Tramadol, Fentany, Oxycodone, Hydrocodone, MDMA, MDA, Amphetamine, Sibutramine, Cocaine, Triptans, LSD, Panax Ginseg, Nutmed, Yohimbe, Syrian Rue, Ritonavir, Granisetron, Olanzapine, Valproate, Buspirone, Lithium, Linezolid, Dextromethorphan, Risperidone, Trypthophan, L-Dopa, Valproate, Amphetamine. Because serotonin syndrome it's not tested in the laboratory for diagnosis, signs or symptoms are the one need noticed. The number one set of criteria to utilize to diagnose serotonin toxicity is Hunter Serotonin Toxicity Criteria.

Treatment for serotonin syndrome are as follows: discontinuing drugs that made the overdose posible and drugs which can contribute management of serotonin antagonist (eg. cyproheptadine) for cut cases of toxicity for agitation, muscular tissue hardness and also capture such as movements, benzodiazepines (Valium, Ativan) Intra venous fluids Because serotonin syndrome is not simple to diagnose, prevention is required for any serotonin drugs combination which may lead to 5-hydroxytryptamine toxicity.


Dunkley, EJ, Isbister, GK, Sibbritt, D, Dawson, AH, Whyte, IM, The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity, QJM 2003; 96:635-642 Prator BC. Serotonin syndrome. J Neurosci Nurs. 2006 Apr;38(2):102-5. Ford MD, Clinical Toxicology. 1st ed. Philadelphia, Pa: WB Saunders; 2001:150, 522, 547, 550.